Jul 27th 2025

Cell Matrix Delivery & Why Bioavailability Matters for Dogs

By Phil Rossi

When it comes to supporting your dog’s health, what goes into a supplement is just as important as how well it’s absorbed. At Pet MatRx, we’re using pharmaceutical-grade technology to ensure that dogs get the most from every dose because if it’s not good enough for humans, it’s not good enough for our pets either.

The Problem with Most Dog Supplements

Many pet supplements are packed with nutrients, but that doesn’t mean your dog is absorbing them. One of the biggest challenges in pet nutrition is bioavailability or how much of an ingredient your dog’s body can actually use.

Lipids: A Common Culprit

Some of the most helpful ingredients in pet health, like Omega-3 fatty acids and Curcumin, fall into a category called lipids. These are fat-based compounds that are naturally difficult for dogs to digest and absorb. In fact, traditional delivery methods often result in your dog using as little as 5% of what’s in a capsule or chew.

So what happens to the other 95%? It’s processed as waste—putting added stress on your dog’s liver and digestive system. Over time, this can contribute to organ fatigue and a buildup of toxins in the body.

Maximizing Bioavailability for Dogs Using PetMatrx Cell Matrix Delivery™ (CMD)

At Pet MatRx, we’ve taken a different approach. Our proprietary Cell Matrix Delivery™ system skips the digestive process and sends nutrients straight to the cells where they’re needed most.

Instead of overloading the liver or gut, ingredients like Curcumin and Omega-3s are made water-compatible and delivered directly into the bloodstream. This dramatically improves absorption and reduces stress on internal organs.

The Science Behind CMD Technology to Maximize Bioavailability for Dogs

If you’re someone who loves to understand how things work, this part is for you.

Lipids are typically nonpolar molecules, which means they don’t dissolve in water. The human (and canine) body, however, is largely water—over 70% in total, and 95% when it comes to blood plasma. So we re-engineer the lipids to carry a polar charge, allowing them to bind with water molecules. This makes them compatible with your dog’s bloodstream.

By attaching lipids to water, we bypass the liver and intestines altogether avoiding what’s known as the “first-pass effect,” where much of an ingredient is broken down before it can do its job.

The result? More of the active ingredient reaches the bloodstream, so your dog actually benefits from what they’re taking.

What About Peptides?

Peptides for dogs and humans are naturally fragile and often ineffective when taken by mouth because they break down in the digestive tract. Traditionally, they’re administered by injection to ensure they reach their target.

Thanks to our CMD technology, we can protect peptides and deliver them orally without degrading their structure. Water molecules shield the peptides as they move into the bloodstream, allowing them to reach the intended area and do their job effectively.

This means more efficient results without the need for injections or complicated routines.

Only the Good Stuff: Human-Grade and All-Natural Supplements for Your Dog

We don’t use fillers, artificial preservatives, or unnecessary ingredients—ever.

Every compound in Pet MatRx products is either:

Found in nature
Naturally produced by your dog’s body
Or bioactive (able to signal or support cellular function)

Even our peptides are selected for their natural roles in recovery, immunity, anti-inflammatory support, and tissue repair. Our formulas are built to work with your dog’s biology—not against it.

Why Bioavailability Should Matter to Every Pet Parent

If you’ve ever invested in a supplement only to wonder whether it’s actually helping your dog, you’re not alone. Without proper delivery, even the best ingredients can go to waste.

That’s why we focus on maximizing absorption, minimizing waste, and targeting specific biological needs. With Pet MatRx, your dog gets science-backed support in every drop—without overwhelming their system.

Want to see the difference for yourself?
Explore how Pet MatRx supports immune health, gut repair, inflammation balance, and more starting at the cellular level.